TAB29 是一种有效的 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) 抑制剂,IC50 值为 874?nM。具有癌症治疗的潜力。
CAS:2361144-71-8
分子式:C28H22O3
分子量:406.47
纯度:98%
存储:Store at -20°C
Background:
TAB29 is a potent inhibitor of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) with an IC50 of 874?nM, possesses therapeutic potential for human cancers[1].
IC50:874?nM (Pin1)[1]
[1]. Fan X, et al. Discovery of 4,6-bis(benzyloxy)-3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis. Bioorg Med Chem. 2019 Jun 1;27(11):2235-2244.