BET-IN-1是溴区酶抑制剂,plC50为6.0-7.0。
CAS：1422554-34-4
分子式：C25H30N4O4
分子量：450.53
纯度：98%
存储：Store at -20°C

Background:

BET-IN-1 is a bromodomain inhibitor extracted from patent WO/2013024104A1, compound example 2, has a plC50 in the range 6.0 - 7.0.IC50 value: 6.0 - 7.0 (plC50)Target: bromodomain

[1]. Demont Emmanuel Hubert, et al. Preparation of 4-(8-methoxy-1-(1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-7-yl)-3,5-dimethylisoxazole, its salts and isomers and their use as bromodomain inhibitors. From PCT Int. Appl. (201