Cyproheptadine is a first-generation antihistamine that potently antagonizes the histamine H1 receptor (pKi = 9.42).
CAS：41354-29-4
分子式：C21H21N.HCl [1.5H2O]
分子量：350.9
纯度：98%
存储：Store at -20°C

Background:

Cyproheptadine is a first-generation antihistamine that potently antagonizes the histamine H1 receptor (pKi = 9.42). It also antagonizes serotonin and muscarinic receptors at nanomolar concentrations. Cyproheptadine also inhibits the lysine methyltransferase SET7/9 (IC50 = 1 µM), suppressing the expression of estrogen receptor α in human breast cancer MCF-7 cells.