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FTI-2153
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FTI-2153图片
CAS NO:344900-92-1
规格:≥98%

FTI-2153 is a potent and selective farnesyltransferase (FTase) inhibitor, with an IC50 of 1.4 nM and with >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing. FTI-2153 inhibits bipolar spindle formation during mitosis independently of transformation and Ras and p53 mutation status. FTI-2153 was reported to block bipolar spindle formation and chromosome alignment and causes prometaphase accumulation during mitosis of human lung cancer cells.

纯度:≥98%

CAS:344900-92-1

 
 
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