CX-5011 is a highly selective and potent inhibitor of protein kinase CK2 (IC50 = 0.175 nM for native CK2), a pro-survival and anti-apoptotic kinase highly expressed in cancer cells.
CAS：1333382-30-1
分子式：C20H11N4O2.Na
分子量：362.3
纯度：98%
存储：Store at -20°C

Background:

CX-5011 is a highly selective and potent inhibitor of protein kinase CK2 (IC50 = 0.175 nM for native CK2), a pro-survival and anti-apoptotic kinase highly expressed in cancer cells. It was highly selective for CK2 over a panel of 235 protein kinases. It induces apoptosis, has anticancer properties in vitro, and appears to overcome the drug resistance phenotype that is partially induced by CK2.