Niperotidine是一种组胺H2受体(histamineH2-receptor)拮抗剂。
CAS：84845-75-0
分子式：C20H26N4O5S
分子量：434.51
纯度：98%
存储：Store at -20°C

Background:

Niperotidine is a histamine H2-receptor antagonist.

Niperotidine (piperonyl-ranitidine) is a H2 blocking agent. Niperotidine is a H2-receptor antagonist structurally related to ranitidine. After oral administration, it reaches a plasmatic peak within 60-120 min and is eliminates either in the urine or in the faeces, with an enterohepatic circulation[2].

[1]. Palasciano G, et al. The effect of the H2-antagonist Niperotidine on intragastric acidity in healthy subjects undergoing 24-hour pH-monitoring. Ital J Gastroenterol. 1990 Oct;22(5):291-4. [2]. Gasbarrini G, et al. Acute liver injury related to the use of Niperotidine. J Hepatol. 1997 Sep;27(3):583-6.