Aristolochic acid B 是马兜铃酸 (AA) 的主要成分之一,来自马兜铃科 (Aristolochiaceae) 分类群的天然产物。 已知马兜铃酸是有效的诱变剂和致癌物质。Aristolochic acid B 在体内表现出比 Aristolochic acid I 更大的致癌风险。
CAS:475-80-9
分子式:C16H9NO6
分子量:311.25
纯度:98%
存储:Store at -20°C
Background:
Aristolochic acid B is one of the major components of Aristolochic acids (AA) which are natural products derived from taxa in the Aristolochiaceae. Aristolochic acid is known to be a potent mutagen and carcinogen. Aristolochic acid B showes more carcinogenic risk than Aristolochic acid A in vivo[1].
[1]. Xing G, et al. Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney. Mutat Res. 2012 Mar 18;743(1-2):52-8.