TIP 39, Tuberoinfundibular Neuropeptide 是一种神经肽,是甲状旁腺激素 2 受体 (PTH2R) 激动剂。TIP 39 在不同物种中是高度保守的。不同物种中的 TIP 39 都可激活腺苷酸环化酶并通过甲状旁腺激素 2 受体 (PTH2R) 提高细胞内钙水平。
CAS:277302-47-3
分子式:C202H325N61O54S
分子量:4504.2
纯度:98%
存储:Store at -20°C
Background:
TIP 39, Tuberoinfundibular Neuropeptide is a neuropeptide and parathyroid hormone 2 receptor (PTH2R) agonist. TIP 39 is highly conserved among species. TIP39 from all species activates adenylyl cyclase and elevates intracellular calcium levels through parathyroid hormone 2 receptor (PTH2R)[1].
[1]. Della Penna K, et al. Tuberoinfundibular peptide of 39 residues (TIP39): molecular structure and activity for parathyroid hormone 2 receptor. Neuropharmacology. 2003 Jan;44(1):141-53.