PAF-AN-1是血小板激活因子受体(PAF)的拮抗剂。
CAS：115621-84-6
分子式：C28H28N2O3
分子量：440.53
纯度：98%
存储：Store at -20°C

Background:

PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.

PAF-AN-1 is extracted from patent EP0469477A1, page 2, line 47[1]. PAF-AN-1 is a 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline analog. PAF-AN-1 inhibits PAF-induced bronchoconstriction and hemoconcentration when administered po to the guinea pig[2].

[1]. EP0469477A1 [2]. Houlihan WJ, et al. Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists. J Med Chem. 1993 Oct 15;36(21):3098-102.