MMP inhibitor,potent and selective
CAS:849773-63-3
分子式:C20H26N2O5S
分子量:406.5
纯度:98%
存储:Store at -20°C
Background:
ARP 101 is a selective MMP-2 inhibitor with IC50 value of 0.81nM.
MMP-2 is an enzyme and involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, as well as in disease processes, such as arthritis and metastasis [1].
ARP 101 shows inhibition of fibrosarcoma HT1080 cell growth in vitro. ARP 101 has shown