AllergenGald4(46-61),chicken是一种鸡蛋白溶菌酶肽。
CAS：62982-31-4
分子式：C72H116N22O29
分子量：1753.82
纯度：98%
存储：Store at -20°C

Background:

Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.

Allergen Gal d 4 (46-61), chicken (HEL(46-61)) contains the immunodominant epitope recognized by mice of the k haplotype. The binding is shown to be specific, with a Kd of approximately 2 uM. The direct binding of a hen egg white lysozyme peptide, Allergen Gal d 4 (46-61), is examined to membrane I-Ak (protein encoded in the A locus of the I region) molecules in the presence of detergent. A number of synthetic peptide derivatives, which do not stimulate our T-cell reactive hybridomas, compete for the binding of Allergen Gal d 4 (46-61) to I-Ak and also inhibit the functional presentation of Allergen Gal d 4 (46-61). Inhibitors include a peptide lacking a tyrosine at position 53 and a peptide corresponding to the autologous lysozyme peptide. Presentation is examined with cells or with supported planar phospholipid membranes bearing only I-Ak and Allergen Gal d 4 (46-61)[1].

[1]. Proc Natl Acad Sci U S A. 1986 Jun;83(12):4509-13.