Epsilon-momfluorothrin是一种合成的I型拟除虫菊酯杀虫剂,可以活化组成性雄甾烷受体(constitutiveandrostanereceptor(CAR)),可诱导大鼠中肿瘤的发生。
CAS:1065124-65-3
分子式:C19H19F4NO3
分子量:385.35
纯度:98%
存储:Store at -20°C
Background:
Epsilon-momfluorothrin is a type I synthetic pyrethroid insecticide, activates constitutive androstane receptor (CAR), and induces hepatocellular tumors in rats[1].
Constitutive androstane receptor[1]
[1]. Okuda Y, et al. Editor’s Highlight: Mode of Action Analysis for Rat Hepatocellular Tumors Produced by the Synthetic Pyrethroid Momfluorothrin: Evidence for Activation of the Constitutive Androstane Receptor and Mitogenicity in Rat Hepatocytes. Toxicol Sci. 2017 Aug 1;158(2):412-430.