PTP1B-IN-1是PTP1B小分子抑制剂，IC50值为1.6mM,常作为类似物衍生的母核。
CAS：612530-44-6
分子式：C8H8N2O3S
分子量：212.23
纯度：98%
存储：Store at -20°C

Background:

PTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 1.6 mM; 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for derivatives synthesis.

[1]. Black E, et al. Structure-based design of protein tyrosine phosphatase-1B inhibitors. Bioorg Med Chem Lett. 2005 May 16;15(10):2503-7. [2]. Vintonyak VV, et al. Using small molecules to target protein phosphatases. Bioorg Med Chem. 2011 Apr 1;19(7):2145-55.