Thielavin A is a fungal metabolite originally isolated from T.
CAS:71950-66-8
分子式:C29H30O10
分子量:538.5
纯度:98%
存储:Store at -20°C
Background:
Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 and the conversion of PGH2 to PGE2 . Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 µM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 µM; Ki = 27.8 µM).