Extracted?from?Euphorbiaceae Euphorbia lathyris dry mature seeds;Store?the?product?in?sealed,?cool?and?dry?condition
CAS:218916-52-0
分子式:C31H38O7
分子量:522.63
纯度:98%
存储:Store at -20°C
Background:
5,15-Diacetyl-3-benzoyllathyrol is one of the lathyrane diterpenoids, that has anti-cancer activity.
5,15-Diacetyl-3-benzoyllathyrol shows anticancer activity in vitro against lung cancer A549 cells and the IC50 values are 34.04±3.99 μM. Furthermore, 5,15-Diacetyl-3-benzoyllathyrol can induce apoptosis in A549 cells via the mitochondrial pathway including loss of mitochondrial potential and release of cytochrome c[1].
参考文献:
[1]. Zhang JY, et al. Structure identification of Euphorbia factor L3 and its induction of apoptosis through the mitochondrial pathway. Molecules. 2011 Apr 15;16(4):3222-31.