DMA trihydrochloride

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	2095832-33-8
规格:	98%
分子量:	577.93

包装与价格：

包装	价格(元)
5mg	询价
50mg	询价
100mg	询价

DMAtrihydrochloride是一种荧光化合物(λex=340nm,λem=478nm)。
CAS：2095832-33-8
分子式：C27H31Cl3N6O2
分子量：577.93
纯度：98%
存储：Store at -20°C

Background:

DMA trihydrochloride is a fluorescent compound (λex=340 nm, λem=478 nm).

The newly synthesized bisbenzimidazole derivatives DMA (6c) is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), breast carcinoma cell line (MCF7) and brain glioma cell line (U87) in comparison to Hoechst. In case of MCF7, the IC50 is observed at 5.3 μM for DMA. The IC50 determined in the case of HeLa is 3.4 μM for DMA[1].

[1]. Singh M, et al. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles. Eur J Med Chem. 2011 Feb;46(2):659-69.