CID1375606是一种孤儿G蛋白偶联受体GPR27的代理激动剂。
CAS：313493-80-0
分子式：C20H14Cl2N2O2
分子量：385.24
纯度：98%
存储：Store at -20°C

Background:

CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27.

CID 1375606 is a GPR27-specific surrogate agonist. GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion[1].

[1]. Dupuis N, et al. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment. Mol Pharmacol. 2017 Jun;91(6):595-608.