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(±)7(8)-EpDPA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(±)7(8)-EpDPA图片
CAS NO:895127-66-9
规格:98%
分子量:344.5
包装与价格:
包装价格(元)
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Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina.
CAS:895127-66-9
分子式:C22H32O3
分子量:344.5
纯度:98%
存储:Store at -20°C

Background:

Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and is increased following dietary supplementation with ω-3 fatty acids. (±)7(8)-EpDPA and other epoxy metabolites of DHA modulate receptor and channel activities to evoke diverse effects, such as promoting vasodilation, inhibiting angiogenesis, and decreasing inflammatory and neuropathic pain. (±)7(8)-EpDPA is a substrate of soluble epoxide hydrolase (KM = 15 µM), which converts it to the corresponding diol.


 
 
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