Loxoprofen是非甾体抗炎化合物。
CAS：68767-14-6
分子式：C15H18O3
分子量：246.3
纯度：98%
存储：Store at -20°C

Background:

Loxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. COX-1|6.5 μM (IC50, in human whole blood)|COX-2|13.5 μM (IC50, in human whole blood)

[1]. Riendeau D, et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1201-3.