Cyclo(RADfK)是选择性α(v)β(3)整合素配体,广泛用于新血管生成的研究,治疗和诊断。
CAS：756500-23-9
分子式：C28H43N9O7
分子量：617.7
纯度：98%
存储：Store at -20°C

Background:

Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.

Cyclo(RADfK) is a negative control for the cyclo (-RGDfK-), the RGD peptide. RGD peptides are modulators of cell adhesion and are recognized by several members of the integrin family[1].

[1]. Srivatsan A, et al. Conjugation of cRGD peptide to chlorophyll a based photosensitizer (HPPH) alters its pharmacokinetics withenhanced tumor-imaging and photosensitizing (PDT) efficacy. Mol Pharm. 2011 Aug 1;8(4):1186-1197.