LFA-1/sICAM interaction inhibitor
CAS：162112-37-0
分子式：C18H17F3N4O2S
分子量：410.41
纯度：98%
存储：Store at -20°C

Background:

RWJ 50271 is an selective inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells)[1].

参考文献:
[1]. Sanfilippo PJ, et al. Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion. J Med Chem. 1995 Mar 31;38(7):1057-9.