K-Ras G12C-IN-3是突变型K-Ras G12C不可逆小分子抑制剂。
CAS:1629268-19-4
分子式:C21H19Cl3N2O3
分子量:453.75
纯度:98%
存储:Store at -20°C
Background:
K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.IC50 value:Target: K-ras G12C inhibitorFor more information, please see the following patent.Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers, and preparation thereofBy Ren, Pingda; Liu, Yi; Li, Liansheng; Feng, Jun; Wu, Tao From PCT Int. Appl. (2014), WO 2014152588 A1 20140925.