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all-trans-4-Oxoretinoic acid(all-trans 4-Keto Retinoic Acid)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
all-trans-4-Oxoretinoic acid(all-trans 4-Keto Retinoic Acid)图片
CAS NO:38030-57-8
规格:98%
分子量:314.42
包装与价格:
包装价格(元)
2mg询价
5mg询价
10mg询价

all-trans-4-Oxoretinoicacid,是维生素A的活性代谢物,可通过作用核维甲酸受体(RARs)来诱导基因转录。
CAS:38030-57-8
分子式:C20H26O3
分子量:314.42
纯度:98%
存储:Store at -20°C

Background:

all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs).


all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs)[1]. all-trans-4-Oxoretinoic acid is a biologically active geometric isomer of retinoic acid (RA) [2].



[1]. Topletz AR, et al. Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids. Mol Pharmacol. 2015;87(3):430-41. [2]. Stahl W, et al. 4-oxo-retinoic acid is generated from its precursor canthaxanthin and enhances gap junctional communication in 10T1/2 cells. Adv Exp Med Biol. 1996;387:121-8.


 
 
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