Primaquine is an established antimalarial drug used in the treatment of persistent liver forms of P. vivax or P. ovale infection for its ability to kill late-stage gametocytes and hypnozoites. In historical terms, this aminoquinoline was the stimulus for the discovery of glucose-6-phosphate (G6P) dehydrogenase deficiency as it induced hemolytic anemia in patients lacking the G6P-metabolizing enzyme. References: Joshi VM, Devarajan PV. Receptor-mediated hepatocyte-targeted delivery of
primaquine phosphate nanocarboplex using a carbohydrate ligand. Drug Deliv Transl
Res. 2014 Aug;4(4):353-64. doi: 10.1007/s13346-014-0200-4. PubMed PMID: 25787067.
纯度:≥98%
CAS:63-45-6