4-Chlorosalicylicacid是一种药物中间体。抑制单酚酶和二苯酚酶活性，IC50值分别为1.89mM和1.10mM。具有有效的抗菌活性。抑制大肠杆菌的MIC为250μg/mL，MBC为500μg/mL。
CAS：5106-98-9
分子式：C7H5ClO3
分子量：172.56
纯度：98%
存储：Store at -20°C

Background:

4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.

4-chlorosalicylic acid could inhibit both the diphenolase activity and the monophenolase activity of mushroom tyrosinase. 4-chlorosalicylic acid has broad-spectrum antimicrobial activity which could inhibits Gram-positive and Gram-negative bacteria and fungi[1].

[1]. Han P, et al. Inhibitory effects of 4-chlorosalicylic acid on mushroom tyrosinase and its antimicrobial activities. 107 (2), 797-803, 2008