HER2/neu (654-662) GP2 是一种由 9 个氨基酸残基组成的多肽,来源于人类表皮生长因子受体 2 HER2/nue (654-662),可诱导 HLA-A2 限制性细胞毒性 T 淋巴细胞 (CTL) 对多种上皮肿瘤发生反应。
CAS:160790-21-6
分子式:C42H77N9O11
分子量:884.11
纯度:98%
存储:Store at -20°C
Background:
HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654-662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers[1][2].
[1]. Sun Y, et al. Observing the temperature dependent transition of the GP2 peptide using terahertz spectroscopy. PLoS One. 2012;7(11):e50306.
[2]. Tanaka Y, et al. Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes. Int J Cancer. 2001 Nov;94(4):540-4.