HFI-142是胰岛素调节性氨基肽酶(IRAP)抑制剂,ki值为2.01μM。
CAS:332164-34-8
分子式:C17H16N2O4
分子量:312.32
纯度:98%
存储:Store at -20°C
Background:
HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor with a ki of 2.01 μM[1].
ki: 2.01 μM (Insulin-regulated aminopeptidase)[1]
[1]. Albiston AL, et al. Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobicpacking point at the active site of insulin-regulated aminopeptidase. Mol Pharmacol. 2010 Oct;78(4):600-7.