LansoprazoleSulfideD4是LansoprazoleSulfide的氘代物。LansoprazoleSulfide是质子泵抑制剂Lansoprazole的活性代谢产物。LansoprazoleSulfide是一种口服活性抗结核药,细胞内的IC50值为0.59µM,肉汤中的IC50值为0.46µM。
货号:ajcx30890
CAS:1216682-38-0
分子式:C16H10D4F3N3OS
分子量:357.39
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1].
[1]. Mdanda S, et al. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent. Biomed Chromatogr. 2017 Dec;31(12).