Boc-NH-PEG3-CH2COOH是一种基于PEG的PROTAClinker，用于合成PROTAC。
货号:ajcx30298
CAS:462100-06-7
分子式:C13H25NO7
分子量：307.34
溶解度:DMF: 5 mg/ml,DMSO: 1 mg/ml,Ethanol: 30 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Vollmer S, et al. Design, Synthesis, and Biological Evaluation of MEK PROTACs. J Med Chem. 2020 Jan 9;63(1):157-162.