Thalidomide-O-C8-COOH 是一种基于 Thalidomide 的，可募集 CRBN 蛋白的 Cereblon 配体。Thalidomide-O-C8-COOH 可通过 linker 与靶蛋白配体连接，形成 PROTAC 分子。
货号:ajcx29732
CAS:2225148-51-4
分子式:C22H26N2O7
分子量：430.45
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1].

[1]. Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1.