DynaMin inhibitory peptide, myristoylated 是一种 DynaMin 抑制剂，可干扰两性霉素与 dynamin 的结合。
货号:ajcx26778
CAS:251634-22-7
分子式:C61H107N19O14
分子量：1330.64
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization. Control Peptide also available.

Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 272 13419 PMID:9148966 |Kittler et al (2000) Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972 PMID:11050117 |Nong et al (2003) Glycine binding primes NMDA receptor internalization. Nature 422 302 PMID:12646920