A cell-permeable fluorescent calcium indicator
货号:ajcx25866
CAS:1070771-36-6
分子式:C51H52N2O23
分子量：1061
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Fluo-2 AM is a cell-permeable fluorescent calcium indicator.^1,2It has been used to measure the activity of the neuropeptide Y₄receptor, as well as to detect intracellular calcium in tetrandine-stimulated primary rabbit corpus cavernosum smooth muscle cells. It binds to calcium (K_d= 290 nM) and displays excitation/emission maxima of 490/515 nm, respectively. Fluo-2 AM is also available in a cell-impermeable form .

1.Sliwoski, G., Schubert, M., Stichel, J., et al.Discovery of small-molecule modulators of the human Y4 receptorPLoS One11(6)e0157146(2016) 2.Liu, J.-H., Chen, J., Wang, T., et al.Effects of tetrandrine on cytosolic free calcium concentration in corpus cavernosum smooth muscle cells of rabbitsAsian J. Androl.8(4)405-409(2006)