An internal standard for the quantification of picaridin
货号:ajcx25480
CAS:N/A
分子式:C12H20D3NO3
分子量：232.3
溶解度:Chloroform: slightly soluble,Methanol: slightly soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Picaridin-d₃is intended for use as an internal standard for the quantification of picaridin by GC- or LC-MS. Picaridin is an insect repellant.^1,2,3It inhibitsA. aegyptiodorant receptor 2 (AaOR2) or AaOR8 in the presence of their odorant activators, indole and octenol, respectively, expressed inXenopusoocytes (IC₅₀s = 1,452 and 1,911 µM, respectively).¹Picaridin reduces the number of entries into a food chamber by femaleD. melanogasterin an olfactory-based choice assay.²It acts synergistically with the non-pyrethroid insecticide pyrimiphos methyl to increase mortality ofA. gambiaeand reduce blood feeding when used at a concentration of 10 g/m²on nets surrounding guinea pig cages.³Formulations containing picaridin have been used as insect repellants against flies, mosquitoes, chiggers, ticks, and fleas.

1.Bohbot, J.D., and Dickens, J.C.Insect repellents: Modulators of mosquito odorant receptor activityPLoS One5(8)1-11(2010) 2.Syed, Z., Pelletier, J., Flounders, E., et al.Generic insect repellent detector from the fruit fly Drosophila melanogasterPLoS One6(3)e17705(2011) 3.Pennetier, C., Corbel, V., Boko, P., et al.Synergy between repellents and non-pyrethroid insecticides strongly extends the efficacy of treated nets against Anopheles gambiaeMalar. J.638(2007)