The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids.
货号:ajcx18936
CAS:N/A
分子式:C25H46O19P3•3Na
分子量:812.5
溶解度:CHCl3:CH3OH:H2O (3:2:1): 10 mg/ml,PBS (pH 7.2): Freely soluble
纯度:98%
存储:Store at -20°C
库存:
现货Background:
The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns is phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PIP2 by PI-specific phospholipase C generates IP3 and diacylglycerol (DAG). The DAG and IP3 produced by this reaction are part of a complex biochemical and signal transduction cascade that is at the frontier of scientific research today.