The phosphatidylinositols (PtdIns) phosphates represent a small precentage of total membrane phospholipids.
货号:ajcx18920
CAS:N/A
分子式:C46H57NO28P4•7NH(C2H5)3
分子量：1818.3
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

The phosphatidylinositols (PtdIns) phosphates represent a small precentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2 can be phosphorylated by phosphatidylinositol (PI)-3-kinase to make PtdIns-(3,4,5)-P3, which initiates an intricate signaling cascade that has been implicated in cancer. PtdIns-(3,4,5)-P3 fluorescein is a fluorescent probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.