PROTAC Bcl-xL ligand-1 是 Bcl-xL 的配体，可用于 PROTAC 的合成。
货号:ajcx36224
CAS:N/A
分子式:C32H29IN4O4S2
分子量：724.63
溶解度:DMSO : 50 mg/mL (69.00 mM; ultrasonic and warming and heat to 60°C)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PROTAC Bcl-xL ligand-1 is a ligand for Bcl-xL that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Chun-Wa Chung, et al. Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chem Biol. 2020 Sep 18;15(9):2316-2323.