GPR34receptorantagonist2(CompoundD2)是GPR34受体拮抗剂，可用于免疫疾病，炎性疾病的研究。
货号:ajcx32076
CAS:907952-06-1
分子式:C31H26ClNO4
分子量：512
溶解度:DMSO: 83.33 mg/mL (162.75 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

GPR34 receptor antagonist 2 (Compound D2) is a GPR34 receptor antagonist. GPR34 receptor antagonist 2 can be used for immune diseases, inflammatory diseases research[1].

Endogenous ligands of GPR34, a G protein-coupled receptor, act on histamine-releasing activity on antigen- or concanavalin A-stimulated rat mast cells and synergize with nerve growth factor on rat mast cells. It is a lipid such as lysophosphatidylserine having the activity of releasing histamine. GPR34 antagonists can be used, for example, for histamine release inhibitors, immune diseases, edema, hyperacidity, etc[1].

[1]. Fumio Ito, et al. Agent for controlling function of gpr34 receptor. WO2006088246 A1.