E3 ligase Ligand-Linker Conjugates 45 包含用于 E3 泛素连接酶的 cIAP 配体和 linker。E3 ligase Ligand-Linker Conjugates 45 可通过 PROTAC 技术合成降解剂。
货号:ajcx13876
CAS:N/A
分子式:C37H48N4O7
分子量：660.8
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

E3 ligase Ligand-Linker Conjugates 45 incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 45 can be used to design PROTAC degrader[1]. cIAP1

[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.