Benzamide-15N

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Benzamide-15N

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

规格:	98%
分子量:	122.13

包装与价格：

包装	价格(元)
500mg	询价
1g	询价

Benzamide-15N (NSC-3114-15N) 是一种 15N 标记的 Benzamide. Benzamide 可抑制 poly(ADP-ribose) polymerase (PARP).
货号:ajcx35954
CAS:31656-62-9
分子式:C7H7 15NO
分子量：122.13
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Benzamide-15N (NSC-3114-15N) is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Cosi C, et al. Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse. Brain Res. 1996;735(2):343-348.