Mal-NH-ethyl-SS-propionic acid 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
货号:ajcx35746
CAS:2128735-24-8
分子式:C12H16N2O5S2
分子量:332.4
溶解度:DMSO : 100 mg/mL (300.84 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Mal-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.