Icapamespib (PU-HZ151) 是一种有效的 HSP90 抑制剂,EC50 值为5 nM. Icapamespib 可以透过血脑屏障。
货号:ajcx35374
CAS:1000999-96-1
分子式:C19H23IN6O2S
分子量:526.39
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Icapamespib (PU-HZ151) is a potent HSP90 inhibitor with an EC50 of 5 nM. Icapamespib is able to cross blood-brain barrier[1].
[1]. Bolaender A, et al. Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system. Nat Commun. 2021;12(1):4669. Published 2021 Aug 3.