PS47

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PS47

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

规格:	98%
分子量:	286.75

包装与价格：

包装	价格(元)
5mg	询价
10mg	询价
25mg	询价
50mg	询价
100mg	询价

PS47 是 PS48 的非活性 E-异构体。PS48 是 PDK1 的激活剂。PS47 可用作 PS48 的阴性对照。
货号:ajcx35124
CAS:1180676-33-8
分子式:C17H15ClO2
分子量：286.75
溶解度:DMSO : 100 mg/mL (348.74 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48[1][2].

PS47 shows very low binding affinity or no binding to PDK1 (Kd>200 µM)[1].

[1]. Hindie V, et, al. Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol. 2009 Oct;5(10):758-64.
[2]. Pastor-Flores D, et, al. PIF-pocket as a target for C. albicans Pkh selective inhibitors. ACS Chem Biol. 2013 Oct 18;8(10):2283-92.