Azido-PEG8-Boc是一种PROTAClinker，属于PEG和Alkyl/ether类，可用于合成PROTAC。
货号:ajcx31972
CAS:1623791-99-0
分子式:C23H45N3O10
分子量：523.62
溶解度:DMSO: 200 mg/mL (381.96 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Garofalo, Antonio, et al. Efficient synthesis of small-sized phosphonated dendrons: potential organic coatings of iron oxide nanoparticles. New Journal of Chemistry (2014), 38(11), 5226-5239.