Antidepressant agent 1 是一种具有抗抑郁作用的吡唑啉-卤素衍生物，也可用于提高体温。
货号:ajcx29116
CAS:67411-41-0
分子式:C16H19BrN2
分子量：319.24
溶解度:DMSO: 8.93 mg/mL (27.97 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Antidepressant agent 1 is a pyrazidole-halogeno-derivative with antidepressant effects. Antidepressant agent 1 also can be used to increase body temperature[1].

Antidepressant agent 1 (compound I) is prepared in 56% yields by reduction of compound II by NaBH4-AcOH. Compound II is obtained by condensation of compound III with BrCH2CH(OBu)2 followed by acid-catalyzed cyclization[1].

[1]. V. I. Shvedov, et al. Synthesis and properties of new analogs of pyrazidole-halogeno-derivatives of 1,10-trimethylene-2-ethyl-1,2,3,4-tetrahydropyrazino [1,2-a]indole. Pharmaceutical Chemistry Journal volume 12, pages633-635(1978).