TL 13-22 是 TL13-12 的阴性对照,是一种有效的 ALK 抑制剂,IC50 为 0.54 nM。 TL 13-22 不会降解细胞中的 ALK。
货号:ajcx27802
CAS:2229036-65-9
分子式:C45H55ClN10O9S
分子量:947.5
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Negative control for TL 13-12 . Displays no degradation of ALK in cell lines. Highly potent inhibitor of ALK (IC50 = 0.54 nM)
Powell et al (2018) Chemically induced degradation of anaplastic lymphoma kinase (ALK). J.Med.Chem. 61 4249 PMID:29660984