A neuropeptide with diverse biological activities
货号:ajcx21528
CAS:N/A
分子式:C27H37D7O2
分子量：407.7
溶解度:Chloroform: Slightly Soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

7α-hydroxy-4-Cholesten-3-one-d₇is intended for use as an internal standard for the quantification of 7α-hydroxy-4-cholesten-3-one by GC- or LC-MS. 7α-hydroxy-4-Cholesten-3-one is a metabolite of 7α-hydroxy cholesterol and an intermediate in the biosynthesis of bile acids.¹Plasma levels of 7α-hydroxy-4-cholesten-3-one positively correlate with the rate of bile acid synthesis in humans and are increased in patients following ileal resection.²

1.Russell, D.W.The enzymes, regulation, and genetics of bile acid synthesisAnnu. Rev. Biochem.72137-174(2003) 2.Axelson, M., Aly, A., and SjÖvall, J.Levels of 7α-hydroxy-4-cholesten-3-one in plasma reflect rates of bile acid synthesis in manFEBS Lett.239(2)324-328(1988)