Pizuglanstat (compound 3) 是一种前列腺素 D 合酶 (prostaglandin D synthase) 抑制剂,对人造血前列腺素 D 合酶的 IC50 为 76 nM。Pizuglanstat 可用于肌再生性疾病研究,例如肌肉营养不良。
货号:ajcx35110
CAS:1244967-98-3
分子式:C27H36N6O4
分子量:508.61
溶解度:DMSO : 12.5 mg/mL (24.58 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Pizuglanstat (compound 3) is a prostaglandin D synthase inhibitor with an IC50 of 76 nM for human hematopoietic prostaglandin D synthases (H-PGDS). Pizuglanstat can be used for myodegenerative disease research, such as muscular dystrophy[1].
[1]. Yoshihiro Urade, et al. Piperazine compound capable of inhibiting prostaglandin D synthase. US8865714B2.