cGAMP disodium (Cyclic GMP-AMP disodium) 是在细菌中发现的第三种环二核苷酸 (CDN)。cGAMP disodium 是一种有效的舌下免疫佐剂，能促进广泛的免疫，包括血清抗 PA 中和和气道分泌物抗 PA SIgA 反应。
货号:ajcx33332
CAS:2407516-83-8
分子式:C20H22N10Na2O13P2
分子量：718.37
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

cGAMP disodium (Cyclic GMP-AMP disodium) is the third cyclic dinucleotide (CDN) to be discovered in bacteria. cGAMP disodium is an effective adjuvant for sublingual vaccination capable of promoting broad immunity including serum anti-PA neutralizing and anti-PA SIgA responses in airway secretions[1][2].

[1]. Wright TA, et al. Second messengers and divergent HD-GYP phosphodiesterases regulate 3’,3’-cGAMP signaling. Mol Microbiol. 2020;113(1):222-236.