Positive allosteric modulator of AMPA receptors
货号:ajcx26944
CAS:191744-13-5
分子式:C13H13NO4
分子量：247.25
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

AMPAkine; positive allosteric modulator of AMPA. Prototypical benzamide which occupies subsite A only. Modulates channel deactivation and desensitization.

Harms et al (2013) Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy. Neuropharmacology 64 45 PMID:22735771 |Timm et al (2011) Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol.Pharmacol. 80 267 PMID:21543522 |Hennegriff et al (1997) Stable expression of recombinant AMPA receptor subunits: binding affinities and effects of allosteric modulators. J.Neurochem. 68 2424 PMID:9166736