A natriuretic peptide
货号:ajcx25564
CAS:1684439-46-0
分子式:C143H244N50O42S4·C2H4O2
分子量：3524.1
溶解度:Water: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Nesiritide is a 32-amino acid natriuretic peptide and recombinant form of human brain natriuretic peptide .¹It increasesex vivovasorelaxation induced by the calcium ionophore A23187 in porcine hearts isolated from a model of acute coronary occlusion when administered as a 2 µg/kg bolus dose followed by 0.01 µg/kg per minute infusion.²Formulations containing nesiritide have previously been used in the treatment of congestive heart failure.

1.Hobbs, R.E., and Mills, R.M.Therapeutic potential of nesiritide (recombinant b-type natriuretic peptide) in the treatment of heart failureExpert Opin. Investig. Drugs8(7)1063-1072(1999) 2.Lazar, H.L., Bao, Y., Siwik, D., et al.Nesiritide enhances myocardial protection during the revascularization of acutely ischemic myocardiumJ. Card. Surg.24(5)600-605(2009)